The book was written according to the CBCS syllabus of B.Sc I, II, III years (Telangana) covering almost all the parameters from different papers of varied subjects. A comprehensive laboratory guide including the glassware description, equipment description, procedures etc. are described. The use of chemicals and their shelf life, reagents preparation as percent, Molar and Normal solutions, Buffers, etc. are also included for the students to learn as basics form one of the important aspects of any practical class. The experimental methods of Ecology, Biochemistry, Cytology, Genetics, Physiology and Biostatistics are given in detail. Therefore, Keeping the importance of all the above subjects, the book was written as per the syllabus (CBCS) framed by the Osmania University. The book is useful for the students of B.Sc., M.Sc. and Ph.D. students across the state and for other universities. As the information furnished is about the basics of the laboratory practices.