One should respect the power of biotechnology and apply it for the benefit of humankind.

Biotechnology in pharmaceutical industry employs techniques of modern molecular biology to help humankind. Pharmaceutical biotechnology works to make manufacturing processes more efficient in industrial production of pharmaceutical products. Biotechnology will transform the industrial sector in much the same way that it has changed the pharmaceutical sector.

Pharmaceutical Industrial Biotechnology companies develop biocatalysts, such as enzymes, to be used in chemical synthesis. Enzymes are proteins produced by all living organisms. In humans, enzymes help digest food, signal cells to turn on and off, and perform other complex functions. Enzymes are characterized according to the compounds they act upon. Some of the most common enzymes are proteases, which break down protein; celluloses, which break down cellulose; lipases, which act on fatty acids and oils; and oils; and amylases, which break starch down into simple sugars. To improve the productivity-to-cost ratio, scientists are modifying genes to increase enzyme productivity in microorganisms commonly used in manufacturing. They also use genetic engineering to make other microbial enzymes that are too expensive or even impossible to cultivate. The biotechnology techniques of protein engineering and directed protein evolution have been used to modify the substrate specificity of enzymes, improve catalytic properties or broaden the reaction conditions under which enzymes can function so that they are more compatible with existing industrial processes. Companies involved in industrial biotechnology are constantly striving to discover and develop high-value enzymes and bioactive compounds that will enhance Current industrial processes.

The present book is an attempt to provide overall information to the readers interested in Pharmaceutical Biotechnology.

Table of Contents..

---

1. Pharmaceutical Biotechnology: An Introduction
2. Biological Genetics and Variations in Characters of Microbes
3. Concepts, Perspectives and Techniques of Microbial Genetic and Protein Engineering
4. Techniques of Recombinant DNA Technology for Production of Biologicals
5. Animal Cell and Tissue Culture
6. Hybridomas Technology and Monoclonal Antibodies
7. Gene Therapy
8. Microbes in Pharmaceutical Industry
9. Development of Industrial Microorganisms
10. Culturing of Industrial Microorganisms
11. Industrial Fermenters
12. Production of Antibiotics
13. Production of Vitamins
14. Production of Ergot Alkaloids
15. Other Primary Metabolites of Pharmaceutical Uses
16. Biotransformation and Steroid Production
17. Biology of Enzymes
18. Production of Enzymes
19. Production of Enzymes By Fermentation
20. Applications of Enzymes
21. Enzyme Immobilization
22. Applications of Immobilized Enzymes
23. Plant Tissue Culture: Basic Concepts
24. Plant Tissue Culture: Methods
25. Protoplast Fusion Technology
26. DNA Isolation and Sequencing
27. Gene Cloning Vector/Plasmid
28. Methods of Gene Transfer
29. Biotechnology Production of Secondary Plant Metabolites
30. Appendix
31. Glossary
32. Subject Index

Table of Contents..

---